RecQ Helicases

A family of structurally-related DNA helicases that play an essential role in the maintenance of genome integrity. RecQ helicases were originally discovered in E COLI and are highly conserved across both prokaryotic and eukaryotic organisms. Genetic mutations that result in loss of RecQ helicase activity gives rise to disorders that are associated with CANCER predisposition and premature aging.

Also Known As:

ATP-Dependent DNA Helicase Q1; ATP-Dependent DNA Helicase Q4; ATP-Dependent DNA Helicase Q5; DNA Helicase Q1; DNA Helicase RecQL; DNA Helicase RecQL4; DNA Helicase, RecQ-like type 2; DNA-Dependent ATPase Q1; RECQL1 Helicase; RTS Helicase; RecQ Family of DNA Helicases; RecQ Protein; RecQ2 Helicase; RecQ3 Helicase; RecQ4 Helicase; RecQ5 Helicase; RecQ5L Helicase; RecQL Helicase; RecQL2 Helicase; RecQL3 Helicase; RecQL4 Helicase; ATP Dependent DNA Helicase Q1; ATP Dependent DNA Helicase Q4; ATP Dependent DNA Helicase Q5; DNA Dependent ATPase Q1; DNA Helicase, RecQ like type 2; Helicase, RECQL1; Helicase, RTS; Helicase, RecQ; Helicase, RecQ2; Helicase, RecQ3; Helicase, RecQ5; Helicase, RecQ5L; Helicase, RecQL; Helicase, RecQL2; Helicase, RecQL3; Helicase, RecQL4; Helicases, RecQ; RecQ Family of DNA Helicase; RecQ Helicase

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Acid Anhydride Hydrolases
      - Adenosine Triphosphatases: 8623
        DNA Helicases: 627
        RecQ Helicases: 389
  - Isomerases: 463
    - DNA Helicases: 627
      - RecQ Helicases: 389

Birgit Groff-Kellermann Selected Research

Birgit Groff-Kellermann Research Topics

Disease

Drug/Important Bio-Agent (IBA)